Blood Quality Diagnostic Device Detects Storage Differences Between Donors

Differences between blood donors and a population sample: implications for case-control studies.

BACKGROUND Selecting appropriate controls for studies of genetic variation in case series is important. The two major candidates involve the use of blood donors or a random sample of the population. METHODS We compare and contrast the two different populations of controls for studies of genetic variation using data from parents enrolled in the Avon Longitudinal Study of Parents and Children (...

Relationship between Blood Serum Progesterone Levels in Cattle Donors and the Yield and Quality of Embryos

Blood serum progesterone (P4) levels in donor cows and heifers at donor selection, superovulation, insemination and embryo recovery were investigated. Significant differences in P4 levels in the investigated donors during superovulatory oestrus insemination were observed. The cows with low levels of P4 at insemination (5.8 ± 1.7 nmol/l) showed a better yield and quality of embryos (P<0.01) comp...

Diagnostic accuracy of blood centers in the screening of blood donors for viral markers

INTRODUCTION Blood transfusion still remains a life saving intervention in almost all healthcare facilities worldwide. Screening of blood donors/blood units is done in almost every blood bank facility before the blood units/blood components are transfused to prevent transfusion-transmissible infections. The kind of testing kits or the methods used by a facility and the technical expertise of th...

The Relationship between HBSAG and HBV DNA in HBV-Infected Blood Donors

A Broad-Spectrum Infection Diagnostic that Detects Pathogen-Associated Molecular Patterns (PAMPs) in Whole Blood

BACKGROUND Blood cultures, and molecular diagnostic tests that directly detect pathogen DNA in blood, fail to detect bloodstream infections in most infected patients. Thus, there is a need for a rapid test that can diagnose the presence of infection to triage patients, guide therapy, and decrease the incidence of sepsis. METHODS An Enzyme-Linked Lectin-Sorbent Assay (ELLecSA) that uses magnet...